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Cambridge IGCSE β€’ Year 11 β€’ Biology

Variation and Selection

Variation, natural selection, adaptation and evolution.

Chapter 18

Verified Curriculum Topic

What is Variation and Selection?

Variation, natural selection, adaptation and evolution.

Variation and Selection matters because it helps students explain living systems with precise vocabulary and clear cause-and-effect reasoning. At Year 11 level, strong performance usually depends on understanding processes, structures, functions, and diagram-based explanations.

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Summary

The One Thing

Inherited variation means that some individuals are better suited to particular environmental conditions than others. Natural selection increases the frequency of advantageous inherited characteristics over successive generations, producing adaptations and causing populations to evolve.

Reactions, Processes and Experiments

What happensEquation or processWhat you observeType
Mutations introduce random changes into genetic material and may produce new alleles.A mutation is a random change in genetic material that can produce a new allele.β€”Genetic source of variation
Alleles are mixed during sexual reproduction.Mixing of alleles during sexual reproduction, including meiosis and fertilisation.β€”Genetic source of variation
Individuals in a population differ in their characteristics.Variation exists.Individuals of the same species show differences in characteristics.Variation
Organisms produce more offspring than can survive, creating competition for resources.Organisms produce more offspring than can survive, creating competition for resources.Competition for resources occurs.Selection pressure
Environmental factors affect survival and reproduction.A selection pressure acts.Some individuals are less likely to survive or reproduce than others.Natural selection
Individuals with advantageous inherited characteristics survive more successfully.Better-adapted individuals survive.Individuals with advantageous inherited characteristics are more likely to survive.Natural selection
Better-adapted individuals leave more offspring.These individuals reproduce more.The advantageous characteristics are passed to more offspring.Natural selection
Advantageous alleles increase in the population over generations.Advantageous alleles become more common over generations.The frequency of the advantageous inherited characteristic increases in the population.Evolution by natural selection
Exercise increases muscle size in an individual.Increased muscle size caused by exercise.Muscle size may increase in the individual.Environmental variation
Antibiotic treatment kills susceptible bacteria while resistant bacteria survive.Resistant bacteria survive antibiotic treatment and reproduce.Resistant bacteria remain after treatment and increase in number.Antibiotic resistance
Antibiotic treatment does not create resistance; it selects bacteria that already possess resistance alleles.Antibiotics do not create resistance because bacteria need it.Resistant bacteria survive treatment.Natural selection
Organisms with desired characteristics are deliberately bred.Selective breeding: deliberate breeding of organisms with desired characteristics to produce offspring with those characteristics.Offspring are more likely to possess the desired characteristics.Artificial selection
Populations become genetically different after isolation and exposure to different selection pressures.A new species may form when populations become isolated, experience different selection pressures, and accumulate genetic differences until they can no longer produce fertile offspring together.The separated populations can no longer produce fertile offspring together.Speciation
A population changes in the value of a measured characteristic.percentage change = (change in value Γ· original value) Γ— 100The percentage increase or decrease in the population is calculated.Population calculation
The proportion of a particular allele in a population is calculated.frequency of an allele = number of copies of the allele Γ· total number of copies of the geneThe allele frequency is obtained as a proportion.Population genetics calculation

Key Terms

  • Variation: Differences in characteristics between individuals of the same species.
  • Genetic variation: Variation caused by differences in genes or alleles, inherited from parents.
  • Environmental variation: Variation caused by conditions such as diet, climate, exercise, disease, or lifestyle.
  • Mutation: A random change in genetic material that can produce a new allele.
  • Continuous variation: Variation with a range of intermediate values, such as height or body mass, usually influenced by several genes and the environment.
  • Discontinuous variation: Variation that falls into distinct categories, often controlled by one or a few genes, such as blood group.
  • Gene: A length of DNA that codes for a protein or influences a characteristic.
  • Allele: An alternative form of a gene.
  • Natural selection: The process in which individuals with advantageous inherited characteristics are more likely to survive and reproduce.
  • Selection pressure: An environmental factor, such as predation, competition, disease, or climate, that affects survival and reproduction.
  • Adaptation: An inherited feature that makes an organism better suited to its environment.
  • Evolution: The change in the inherited characteristics of a population over successive generations.
  • Population: All the organisms of one species living in the same area at the same time.
  • Species: A group of organisms that can reproduce with one another to produce fertile offspring.
  • Selective breeding: The deliberate breeding of organisms with desired characteristics to produce offspring with those characteristics.
  • Antibiotic resistance: The ability of bacteria with resistance alleles to survive antibiotic treatment and reproduce.
  • Fossil: The preserved remains or traces of organisms from the past, providing evidence for evolution.
  • Extinction: The permanent disappearance of a species when no living individuals remain.

Easily Confused

  • Genetic variation vs environmental variation: Genetic variation is inherited through differences in genes or alleles, whereas environmental variation results from conditions such as diet, exercise or climate and is generally not inherited.
  • Mutation vs adaptation: A mutation is a random genetic change that may produce a new allele; an adaptation is an inherited feature that improves survival and reproduction in a particular environment.
  • Continuous variation vs discontinuous variation: Continuous variation has a range of intermediate values, such as height or body mass; discontinuous variation falls into distinct categories, such as blood group.
  • Natural selection vs selective breeding: Natural selection occurs through environmental pressures, whereas selective breeding is deliberately controlled by humans.
  • Adaptation vs evolution: An adaptation is an inherited feature that improves suitability to an environment; evolution is the change in inherited characteristics of a population over successive generations.
  • Individual organisms vs populations: Individuals do not evolve during their lifetimes; evolution affects populations over many generations.
  • Antibiotic resistance vs antibiotics creating resistance: Antibiotics select resistant bacteria that already possess resistance alleles; they do not create resistance because bacteria need it.
  • Species formation vs extinction: A new species forms when isolated populations become unable to produce fertile offspring together; extinction occurs when no living individuals of a species remain.
  • Inherited characteristics vs acquired characteristics: Natural selection can increase the frequency of inherited characteristics, but acquired features such as increased muscle size caused by exercise are not passed genetically to offspring.

What Gets Asked

  • Explain the causes of variation, distinguishing genetic variation produced by mutations and the mixing of alleles during meiosis and fertilisation from environmental variation such as exercise, diet, climate, disease and lifestyle. A common error is to treat increased muscle size caused by exercise as inherited.
  • Describe the sequence of natural selection: variation exists, a selection pressure acts, better-adapted individuals survive, they reproduce more, and advantageous alleles become more common over generations. Marks are lost if organisms are described as consciously developing features because they need them.
  • Explain antibiotic resistance using the specific mechanism that resistant bacteria survive antibiotic treatment and reproduce. Antibiotics do not create resistance.
  • Identify and explain adaptations as structural, physiological or behavioural, using thick fur, producing concentrated urine and migration respectively. The characteristic must be inherited for natural selection to increase its frequency.
  • Use the equations percentage change = (change in value Γ· original value) Γ— 100 and frequency of an allele = number of copies of the allele Γ· total number of copies of the gene. The relevant change, original value, or total number of gene copies must not be confused.
  • Explain evidence for evolution and the formation of new species, including fossils, similarities in body structures, similarities in DNA and proteins, observed changes such as antibiotic resistance, and isolation followed by different selection pressures and accumulation of genetic differences. Darwin and Wallace independently proposed natural selection as an explanation for evolution in the nineteenth century.

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Syllabus-verified

Learning objectives

  • 18.1Distinguish between continuous and discontinuous variation, giving examples of each.
  • 18.2Describe genetic and environmental causes of variation between individuals of the same species.
  • 18.3Define mutation as a change in the DNA/genetic material of an organism, and state that mutations are a source of variation.
  • 18.4Explain how a mutation can be beneficial, neutral, or harmful to an organism.extended
  • 18.5Explain the process of natural selection, using the terms variation, selection pressure, and survival advantage.extended
  • 18.6Describe an example of natural selection, such as antibiotic resistance in bacteria or pesticide resistance in insects.
Syllabus-verified

Practice questions

Q1. Which of these is an example of continuous variation?1 mark Β· core
  • A. Blood group
  • B. Height in humans
  • C. Ability to roll the tongue
  • D. Sex

Answer: B

  • β€’ 1 mark for selecting B

Height shows a full range of values influenced by many genes and the environment, so it is continuous. Blood group, tongue-rolling, and sex fall into distinct, discrete categories (discontinuous).

Q2. Explain how natural selection leads to a population of insects becoming resistant to a pesticide.4 marks Β· extended

Answer: Variation exists in the population, with some insects naturally more resistant to the pesticide; the pesticide is a selection pressure that kills non-resistant insects; resistant insects survive and reproduce, passing on the resistance allele, so the proportion of resistant insects increases over generations.

  • β€’ 1 mark: variation exists in the population β€” some insects are naturally more resistant
  • β€’ 1 mark: the pesticide acts as a selection pressure
  • β€’ 1 mark: resistant insects survive and reproduce, passing on the resistant allele
  • β€’ 1 mark: the proportion of resistant insects in the population increases over successive generations
Q3. Define mutation.2 marks Β· core

Answer: A change in the amount, arrangement, or structure of the DNA of an organism.

  • β€’ 1 mark: a change in the DNA / genetic material of an organism
  • β€’ 1 mark: stated as a source of variation
Q4. State one genetic and one environmental cause of variation between two plants of the same species.2 marks Β· core

Answer: Genetic: the plants may have inherited different alleles from their parents. Environmental: they may have received different amounts of light, water, or nutrients.

  • β€’ 1 mark: valid genetic cause (different alleles/genes inherited)
  • β€’ 1 mark: valid environmental cause (e.g. light, water, nutrient availability)

Key ideas to master

  • Master the important terms, labelled structures, and process sequences in Variation and Selection.
  • Explain how the system works step by step using accurate biological vocabulary.
  • Practise diagram-based recall, comparisons, and function-based questions.
  • Focus on causes, effects, and interactions rather than memorising isolated points.

Common exam prompts

  • Describe the process or structure in Variation and Selection in the correct sequence.
  • Label or explain a likely diagram-based question from this topic.
  • Compare related systems, tissues, organs, or processes where the chapter requires it.
  • Summarise the functional importance of Variation and Selection in concise exam language.

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What is Variation and Selection in Cambridge IGCSE Year 11 Biology?

Variation, natural selection, adaptation and evolution.

How should I study Variation and Selection effectively?

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